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The Science

The Science : Efficacy

Starch Management

In order to evaluate the efficacy of InSea2® on blood sugar levels following a starch-rich meal, a clinical trial has been realised. Twenty-three healthy participants (11 men, 12 women) aged 19-59 years were recruited in this double-blind, randomized, placebo-controlled crossover study. Participants were given a source of starch (2 slices of white bread) 30 minutes after intake of 500 mg of InSea²® or placebo. Blood glucose and insulin levels were measured for 3 hours and the effect of InSea²® on the glycemic response to the test food has been evaluated. After one week of washout, participants were tested again with the same methodology, but after intake of the alternate study product (cross-over design).

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Table Sugar Management

The present study seeks to further investigate the α-glucosidase inhibitory activity of InSea2®. As α -glucosidase digests disaccharides like table sugar, this food has been chosen to examine this property of InSea2®. This study has been undertaken according to a randomized crossover placebo controlled design where each participant was subjected to two 50 g sucrose tolerance test in a double blind fashion. The 50 g sucrose on each occasion was provided as a lemon-flavored beverage containing InSea2® or not. Each test was separated by at least 2 weeks. Blood glucose and insulin levels were measured for 3 hours and the effect of InSea²® on the glycemic response to the test food has been evaluated.

Published Articles

Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo

A randomised crossover placebo-controlled trial investigating the effect of brown seaweed (Ascophyllum nodosum and Fucus vesiculosus) on postchallenge plasma glucose and insulin levels in men and women